Center for Cancer Biology Research CoBRE

Researching Cancer in the Upper Midwest

The Center for Cancer Biology Research fosters a collaborative and supportive environment for its innovative cancer research laboratories. Researchers here work toward reducing the immense burden of cancer in South Dakota and across the Upper Midwest by translating basic discoveries into clinical trials for human cancer patients.

How We’re Funded

The NIH National Institute of General Medical Sciences funds the Center for Cancer Biology. The goal of this grant is to support a Center of Biomedical Research Excellence (CoBRE) as a foundation for basic science and translational cancer researchers.

What We Research

We focus our research on uncovering the basic mechanisms underlying the development of cancer, understanding the importance of the immune system and in turn developing novel approaches to treat cancer. The center has strengths and expertise in:

• Pediatric brain tumors
• Osteosarcoma
• Leukemia
• Head and neck cancers
• Breast cancer

Our robust oncology clinical trial program includes immunotherapy trials that harness the power of the immune system to destroy tumors. It also includes physician-initiated trials.

How We Support the Scientific Community

The center supports and mentors junior investigators (project leaders) researching the importance of the immune system in head and neck squamous cell carcinoma and childhood cancers. The leadership team provides project leaders with an individualized mentorship plan to enhance their professional skills and further their research goals to become successful, independent investigators.

The Center also supports two interdisciplinary cores:

1. Flow Cytometry Core
2. Histology & Imaging Core

These provide center affiliates and regional scientists with key expertise and access to the latest technologies.

Our Publications

To learn more about the research center, see the published research under its CoBRE grant.

Real All Publications